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Dosing Study of Remifentanil for Smooth Removal of the Laryngeal Mask Airway (LMA)

Information source: Ajou University School of Medicine
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Drug Usage

Intervention: remifentanil (Drug); laryngeal mask airway (LMA) (Device)

Phase: Phase 4

Status: Completed

Sponsored by: Ajou University School of Medicine

Official(s) and/or principal investigator(s):
Jong Yeop Kim, MD, Study Director, Affiliation: Ajou University School of Medicine


The investigators attempted to determine the optimal effect-site concentration of remifentanil for smooth removal of the LMA from propofol anesthesia.

Clinical Details

Official title: Effect-site Concentration of Remifentanil for Smooth Removal of the LMA From Propofol Anesthesia

Study design: Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Primary outcome: smooth removal of LMA

Detailed description: At the end of the surgery, propofol infusion was stopped and remifentanil was titrated to predetermined (initial concentration 1. 0 ng/ml for the first patient). LMA removal was performed when the patients opened their eyes and spontaneous respiration and adequate tidal volume and ventilatory frequency were confirmed.


Minimum age: 18 Years. Maximum age: 60 Years. Gender(s): Both.


Inclusion Criteria:

- ASA I-II patients undergoing general anesthesia for short elective surgery (<1 hr)

Exclusion Criteria:

- G-E reflux

- obesity (BMI>30)

- anticipated difficult airway

Locations and Contacts

Ajou University School of Medicine, Suwon 443-721, Korea, Republic of
Additional Information

Starting date: October 2013
Last updated: October 13, 2014

Page last updated: August 23, 2015

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