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Efficacy of Popliteal Nerve Blocks With and Without Dexamethasone on the Duration of Analgesia for Foot & Ankle Surgery

Information source: Cedars-Sinai Medical Center
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Foot and Ankle Procedures

Intervention: Dexamethasone (Drug); Saline (Drug)

Phase: Phase 4

Status: Completed

Sponsored by: Cedars-Sinai Medical Center

Official(s) and/or principal investigator(s):
Roya Yumul, MD, Principal Investigator, Affiliation: Cedars-Sinai Medical Center


The purpose of this research study to evaluate the effects of dexamethasone as an addition to peripheral nerve block (Put the nerve to sleep with Bupivacaine a numbing medication) on length of pain relief (analgesia), postoperative narcotic (opioids) requirements, pain scores, and patient satisfaction after foot and ankle procedures.

Clinical Details

Official title: Prospective Randomized Double Blind Study to Evaluate the Efficacy of Popliteal Nerve Blocks With and Without Dexamethasone on the Duration of Analgesia for Foot & Ankle Surgery.

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Primary outcome: Postoperative pain using a Verbal Rating Scale

Secondary outcome:

Nausea and vomiting will be measured with follow up

patient satisfaction

Opioid consumption

length of analgesia


Minimum age: 18 Years. Maximum age: 90 Years. Gender(s): Both.


Inclusion Criteria:

- 100 patients (50 per group) undergoing foot and ankle procedures

- Willingness and ability to sign an informed consent document

- No allergies to anesthetic or analgesic medications

- American Society of Anesthesiologists (ASA)physical status Class I - III

- Aged 18-90 years,either sex

Exclusion Criteria:

- Refusal to participate in the study

- Age<18 or> 90 years -

- Contraindications to regional blockage including but not limited to:

- Patient refusal to regional blockade

- Infection at the site of needle insertion

- Systemic infection

- Bleeding diathesis or coagulopathy

Locations and Contacts

Cedars Sinai Medical center, Los Angeles, California 90048, United States
Additional Information

Starting date: August 2013
Last updated: February 26, 2015

Page last updated: August 23, 2015

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