Intrathecal Morphine,Femoral Nerve Block,Periarticular Bupivacaine Infiltration for Pain After Intramedullary Hip Screw
Information source: Mahidol University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Femoral Neck Fractures
Intervention: Bupivacaine, morphine (Drug)
Phase: Phase 4
Status: Recruiting
Sponsored by: Mahidol University Official(s) and/or principal investigator(s):
Thitima Chinachoti, M.D., Principal Investigator, Affiliation: Mahidol University
Overall contact:
Thitima Chinachoti, M.D., Phone: 66813082438, Email: sitci35@gmail.com
Summary
Falls are a common problem in elderly patients resulting fractured femur, which require
early operation. Adequate postoperative pain control will provide good recovery. The
investigators will compare the efficacy of postoperative pain control among intrathecal
morphine, femoral nerve block, and periarticular infiltration with bupivacaine in patients
undergone intramedullary hip screw under spinal anesthesia.
Clinical Details
Official title: Post Operative Pain Control Among Intrathecal 0.1 mg Morphine, Femoral Nerve Block, or Periarticular Infiltration of 20 mL of 0.25% Bupivacaine in Patients Post Intramedullary Hip Screw
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: The amount of morphine consumption.
Secondary outcome: Efficacy of pain control
Detailed description:
Study methods :
Every patients without any exclusion criteria will be performed spinal anesthesia by 0. 5%
heavy bupivacaine then divided into 4 groups
1. Controlled group : spinal anesthesia alone
2. Femoral nerve block by 20 mL of 0. 25% bupivacaine before spinal anesthesia
3. Spinal anesthesia plus 0. 1 mg morphine intrathecally
4. Spinal anesthesia plus periarticular infiltration with 20 mL of 0. 25% bupivacaine
All patients will receive postoperative intravenous patient controlled analgesia (IV PCA)
morphine for 48 hours.
Data collection
1. Demographic data
2. Pain score : preoperative, 3 hours postoperative in the 1st six hours, 12 hours
postoperative by visual analog scoring system (VASS)
3. Patient global assessment and patient satisfactory VASS at 24 and 48 hours
postoperative
4. The amount of morphine at 24 and 48 hours postoperative and the time of the 1st dose
Eligibility
Minimum age: 18 Years.
Maximum age: 90 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- 18-90 years old
- good consciousness, well co-operated, can use PCA machine
- ASA class 1-3
- no contraindication of spinal anesthesia
- accept for spinal anesthesia
- body weight > 30 kg
- BMI 20-35 kg/m2
- no history of research-drug allergy
Exclusion Criteria:
- previous history of hip surgery (the same side)
- pathological fractured such as severe infection, bone cancer
Locations and Contacts
Thitima Chinachoti, M.D., Phone: 66813082438, Email: sitci35@gmail.com
Faculty of Medicine Siriraj Hospital, Bangkok 10700, Thailand; Recruiting
Thitima Chinachoti, MD, Phone: 6681-3082438, Email: sitci35@gmail.com
Thitima Chinachoti, MD, Principal Investigator
Additional Information
Starting date: September 2010
Last updated: August 3, 2011
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