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Chicago Social Drinking Project

Information source: University of Chicago
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Alcoholism

Intervention: Ethanol (Drug); Placebo (Drug); Diphenhydramine (Drug); Caffeine (Drug)

Phase: N/A

Status: Active, not recruiting

Sponsored by: University of Chicago

Official(s) and/or principal investigator(s):
Andrea C King, PhD, Principal Investigator, Affiliation: University of Chicago


This study attempts to elucidate the factors that contribute to escalation and maintenance of excessive ethanol drinking in young adults by: 1. Examining subjective and objective response differences to alcohol and other common substances in a sample of young, adult social drinkers with varying consumption patterns. 2. Determining whether response to alcohol and other substances is predictive of future consumption patterns through longitudinal follow-up interviews. 3. Examining the relationship between responses to alcohol and other substances at baseline and re-examination testing to evaluate if consumption patterns moderate this relationship.

Clinical Details

Official title: Individual Differences After Consumption of Alcohol and Other Common Substances and Long-Term Follow-Up of Social Drinking, Young Adults

Study design: Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Screening

Primary outcome: Subjective response to alcohol and other common substances utilizing mood questionnaires in social drinking young adults

Secondary outcome: Substance Use Behavior Reported During Follow-Up Interviews


Minimum age: 21 Years. Maximum age: 29 Years. Gender(s): Both.


Inclusion Criteria:

- Age 21-29

- Weigh between 110-210 lbs

- Drink alcohol at least once weekly with weekly "binge" drinking episodes

- Available to complete in-person screening and 2, 4 hour experimental sessions at the

University of Chicago

- Available by phone, mail, or Internet for follow-up interviews for at least 2 years

following sessions Exclusion Criteria:

- Current or past major medical or psychiatric disorders including alcohol and

substance dependence

Locations and Contacts

Clinical Addictions Research Laboratory, Chicago, Illinois 60637, United States
Additional Information

Study Website

Related publications:

King AC, Byars JA. Alcohol-induced performance impairment in heavy episodic and light social drinkers. J Stud Alcohol. 2004 Jan;65(1):27-36.

King AC, Houle T, de Wit H, Holdstock L, Schuster A. Biphasic alcohol response differs in heavy versus light drinkers. Alcohol Clin Exp Res. 2002 Jun;26(6):827-35.

Starting date: March 2004
Last updated: March 4, 2015

Page last updated: August 23, 2015

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