Ultrasound-guided Blocks for Ambulatory Knee Arthroscopy
Information source: Bispebjerg Hospital
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Postoperative Pain; Postoperative Nausea and Vomiting; Postoperative Function Level
Intervention: Block of the SN and ONP (Procedure); Placebo block (Procedure); Paracetamol (Drug); Morphine (Drug); Ondansetron (Drug); Metoclopramide (Drug)
Phase: Phase 4
Status: Completed
Sponsored by: Jens Borglum Neimann Official(s) and/or principal investigator(s): Bo Westergaard, MD, Principal Investigator, Affiliation: Department of Anesthesiology, Bispebjerg Hospital
Summary
In this study, we wish to investigate the effect of ultrasound (US) - guided block of the
saphenous nerve (SN) and the posterior branch of the obturator nerve (ONP) on postoperative
pain and the use of opioids (morphine-like pain medicine) in the first 24 hours following
ambulatory knee arthroscopy.
We wish to investigate the analgesic effect of these two blocks compared to placebo
(injection of local anesthetic with known pain blocking properties compared with injection
of a saline solution), when used as a supplement to conventional oral analgesics.
We hypothesize that patients receiving the active treatment may experience less pain during
the first 24 hours after their operation than patients receiving the placebo treatment, and
possibly require less opioid analgesics, experience less opioid related side effects and
have a higher function level in this period than patients receiving the placebo treatment.
Clinical Details
Official title: Ultrasound-guided Block of the Saphenous Nerve and Obturator Nerve, Posterior Branch, for Postoperative Pain Management After Ambulatory Knee Arthroscopy
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: Pain on knee flexion
Secondary outcome: Pain at restTime to opioid intake Total opioid intake Nausea Vomiting Use of antiemetics PACU length of stay Function level: Barthel Index/100 Function level: Short form (SF) -8
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Planned ambulatory knee arthroscopy, except cruciate ligament surgery
- American Society of Anesthesiologists (ASA) class 1-3
Exclusion Criteria:
- Cannot cooperate
- Do not speak or understand Danish
- Daily use of opioid analgesics
- Allergy towards any of the drugs used in the investigation
- Medicine abuse (at the investigators discretion)
- Alcohol abuse, as defined by the National Board of Health
- General anesthesia contraindicated, or the patient wants spinal anesthesia
- Visualization of necessary structures by ultrasound not possible, or block not
possible for other technical reasons
Locations and Contacts
Department of Anesthesiology, Bispebjerg Hospital, Copenhagen 2400, Denmark
Additional Information
Starting date: August 2012
Last updated: November 5, 2013
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