DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more



Ultrasound-guided Blocks for Ambulatory Knee Arthroscopy

Information source: Bispebjerg Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Postoperative Pain; Postoperative Nausea and Vomiting; Postoperative Function Level

Intervention: Block of the SN and ONP (Procedure); Placebo block (Procedure); Paracetamol (Drug); Morphine (Drug); Ondansetron (Drug); Metoclopramide (Drug)

Phase: Phase 4

Status: Completed

Sponsored by: Jens Borglum Neimann

Official(s) and/or principal investigator(s):
Bo Westergaard, MD, Principal Investigator, Affiliation: Department of Anesthesiology, Bispebjerg Hospital

Summary

In this study, we wish to investigate the effect of ultrasound (US) - guided block of the

saphenous nerve (SN) and the posterior branch of the obturator nerve (ONP) on postoperative pain and the use of opioids (morphine-like pain medicine) in the first 24 hours following ambulatory knee arthroscopy. We wish to investigate the analgesic effect of these two blocks compared to placebo (injection of local anesthetic with known pain blocking properties compared with injection of a saline solution), when used as a supplement to conventional oral analgesics. We hypothesize that patients receiving the active treatment may experience less pain during the first 24 hours after their operation than patients receiving the placebo treatment, and possibly require less opioid analgesics, experience less opioid related side effects and have a higher function level in this period than patients receiving the placebo treatment.

Clinical Details

Official title: Ultrasound-guided Block of the Saphenous Nerve and Obturator Nerve, Posterior Branch, for Postoperative Pain Management After Ambulatory Knee Arthroscopy

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: Pain on knee flexion

Secondary outcome:

Pain at rest

Time to opioid intake

Total opioid intake

Nausea

Vomiting

Use of antiemetics

PACU length of stay

Function level: Barthel Index/100

Function level: Short form (SF) -8

Eligibility

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Planned ambulatory knee arthroscopy, except cruciate ligament surgery

- American Society of Anesthesiologists (ASA) class 1-3

Exclusion Criteria:

- Cannot cooperate

- Do not speak or understand Danish

- Daily use of opioid analgesics

- Allergy towards any of the drugs used in the investigation

- Medicine abuse (at the investigators discretion)

- Alcohol abuse, as defined by the National Board of Health

- General anesthesia contraindicated, or the patient wants spinal anesthesia

- Visualization of necessary structures by ultrasound not possible, or block not

possible for other technical reasons

Locations and Contacts

Department of Anesthesiology, Bispebjerg Hospital, Copenhagen 2400, Denmark
Additional Information

Starting date: August 2012
Last updated: November 5, 2013

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017