Effects of Addition of Magnesium Sulfate in Spinal Anesthesia on Sensory-Motor Blocks and Postoperative Pain in Lumbar Disk Herniation Surgery
Information source: Isfahan University of Medical Sciences
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Lumbar Spine Disc Herniation
Intervention: Magnesium Sulfate (Drug); Spinal Anesthesia (Procedure); Bupivacaine (Drug); Fentanyl (Drug)
Phase: Phase 4
Status: Completed
Sponsored by: Isfahan University of Medical Sciences Official(s) and/or principal investigator(s):
Mohammad Ali Attari, MD, Study Chair, Affiliation: Isfahan University of Medical Sciences
Summary
The purpose of this study is to Compare three methods of intrathecal bupivacaine;
bupivacaine-fentanyl; bupivacaine-fentanyl-magnesium sulfate on sensory-motor blocks and
postoperative pain in patients undergoing lumbar disk herniation surgery.
Clinical Details
Official title: Comparison of the Effects of Three Methods of Intrathecal Bupivacaine; Bupivacaine-Fentanyl and Bupivacaine-Fentanyl-Magnesium Sulfate on Sensory-Motor Blocks and Postoperative Pain in Patients Undergoing Lumbar Disk Herniation Surgery
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Supportive Care
Primary outcome: The onset of sensory blockThe complete motor block The sensory block regression The full motor recovery The Pain Score Time to first analgesic requirement
Secondary outcome: Mean Arterial Blood PressureHeart Rate
Detailed description:
- Comparison three methods of intrathecal
bupivacaine;bupivacaine-fentanyl;bupivacaine-fentanyl-magnesium sulfate on
sensory-motor blocks in patients undergoing lumbar disk herniation surgery
- Comparison three methods of intrathecal
bupivacaine;bupivacaine-fentanyl;bupivacaine-fentanyl-magnesium sulfate on
postoperative pain in patients undergoing lumbar disk herniation surgery
- Comparison three methods of intrathecal
bupivacaine;bupivacaine-fentanyl;bupivacaine-fentanyl-magnesium sulfate on
postoperative side effects in patients undergoing lumbar disk herniation surgery
Eligibility
Minimum age: 20 Years.
Maximum age: 65 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Candidate for lumbar disk herniation surgery
- No contraindication to the spinal anesthesia
- No history of allergy to opioids and magnesium sulfate
- No peripheral or central neuropathies
- No previous history of surgery on same disk level
Exclusion Criteria:
- Patients with intraoperative tearing of dural suc
- Occuring of inadvertent intraoperative complications such as bleeding
Locations and Contacts
Alzahra, Isfahan, Iran, Islamic Republic of
Additional Information
Starting date: November 2012
Last updated: June 30, 2013
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