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Dexamethasone for Preterm Labour

Information source: Assiut University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Prematurity

Intervention: Dexamethasone 24 hours (Drug); Dexamethasone 12 (Drug)

Phase: Phase 2

Status: Completed

Sponsored by: Assiut University

Summary

The investigators sought to determine whether the incidence of neonatal respiratory distress syndrome (RDS) in preterm fetuses is similar with 12- vs 24-hour dosing interval of dexamethasone.

Clinical Details

Official title: Dexamethasone Dosing Interval: 12 or 24 Hours Apart? A Randomized,Clinical Trial

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Primary outcome: respiratory distress syndrome (RDS)

Secondary outcome: Perinatal mortality

Detailed description: The administration of glucocorticoids to accelerate fetal lung maturity in patients with preterm delivery plays an important role for obstetrics and neonatal care. Many studies have shown that maternal administration of glucocorticoids has a significant beneficial effect in decreasing the incidence of respiratory distress syndrome (RDS) in infants delivered at 28-34 weeks of gestation.

Eligibility

Minimum age: 20 Years. Maximum age: 40 Years. Gender(s): Female.

Criteria:

Inclusion Criteria:

- All patient with threatened or established preterm labor between 28 - 34 weeks

attended to our emergency unit Exclusion Criteria:

- emergent obstetric conditions like:

- Antepartum hemorrhage in severe attack

- Antepartum eclampsia

Locations and Contacts

Women Health Hospital - Assiut university, Assiut 71111, Egypt
Additional Information

Starting date: January 2012
Last updated: September 28, 2012

Page last updated: August 23, 2015

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