Laryngeal Mask Airway (LMA) Insertion With Sevoflurane and Remifentanil
Information source: Gachon University Gil Medical Center
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Laryngismus
Intervention: Remifentanil 1 (Drug); Control (Drug); Remifentanil 2 (Drug)
Phase: N/A
Status: Completed
Sponsored by: Gachon University Gil Medical Center Official(s) and/or principal investigator(s):
Jong Yeop Kim, MD,PhD, Study Director, Affiliation: Ajou University School of Medicine
Jong Yeop Kim, MD, PhD, Study Director, Affiliation: Ajou Universiy School of Medicine
Summary
The purpose of this study was to determine the most suitable effect-site concentration of
remifentanil for the LMA insertion during inhaled induction with 8% sevoflurane in adults.
Clinical Details
Official title: Target-controlled Infusion of Remifentanil for Laryngeal Mask Airway Insertion During Sevoflurane Induction in Adults
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator)
Primary outcome: LMA Insertion Condition
Secondary outcome: Frequency of Apnea
Detailed description:
For practical purposes, opioids with the ability to suppress upper airway reflexes have been
used to facilitate insertion of the LMA during anaesthesia induction. To date, however,
there have been no published reports addressing the use of remifentanil to facilitate LMA
insertion during sevoflurane inhalation induction in adults. Therefore, the purpose of this
study was to determine the most suitable effect-site concentration of remifentanil
target-controlled infusion (TCI) for the LMA insertion during inhaled induction with 8%
sevoflurane in adults.
Eligibility
Minimum age: 18 Years.
Maximum age: 60 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Adult patients, aged 18-60 with ASA physical status I or II, who were scheduled to minor
elective surgery (< 1 h) were considered for the study
Exclusion Criteria:
- Exclusion criteria were allergies to the study drugs, a history of gastric reflux, a
history of drug abuse, obesity (body mass index > 30 kg/m2) and suspected difficult airway
Locations and Contacts
Ajou University School of Medicine, Suwon, Korea, Republic of
Additional Information
Related publications: Sivalingam P, Kandasamy R, Madhavan G, Dhakshinamoorthi P. Conditions for laryngeal mask insertion. A comparison of propofol versus sevoflurane with or without alfentanil. Anaesthesia. 1999 Mar;54(3):271-6.
Starting date: April 2011
Last updated: April 17, 2014
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